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Chemistry news archive 2007


March 2007


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Nanoscale calcium silicate hydrate

Novel Experiments on Cement Yield Concrete Results

Using a brace of the most modern tools of materials research, a team from the National Institute of Standards and Technology (NIST) and Northwestern University has shed new light on one of mankind’s older construction materials - cement. Their refinements to our understanding of how cement and concrete actually work, reported this week in Nature Materials, ultimately may make possible improvements in the formulation and use of cement that could save hundreds of millions of dollars in annual maintenance and repair costs for concrete structures and the country’s infrastructure.

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Protein averts cell suicide but might contribute to cancer

Scientists have discovered how an unusual protein helps a cell bypass damage when making new DNA, thereby averting the cell's self-destruction.

But they also discovered that this protein, an enzyme called Dpo4, often makes errors when copying the genomic DNA sequence that later might cause the cell to become cancerous.

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Titanium Dioxide - It Slices, It Dices ...
Chemists have proposed an elegantly simple technique for cleaving proteins into convenient pieces for analysis.

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A sweet step toward new cancer therapies
By recognizing sugars, a technique developed by University of Michigan analytical chemist Kristina Hakansson sets the stage for new cancer diagnosis and treatment options.

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Traces of Nanobubbles Determine Nano-boiling
Using a microscope and some extreme “snapshot” photography with shutter speeds only a few nanoseconds long, researchers from NIST and Cornell University have uncovered the traces of ephemeral “nanobubbles” formed in boiling water on a microheater.

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Cells selectively absorb short nanotubes
DNA-wrapped single-walled carbon nanotubes (SWCNTs) shorter than about 200 nanometers readily enter into human lung cells and so may pose an increased risk to health, according to scientists at NIST.

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New metal crystals, formed on a cotton assembly line
First appearance of silver, gold, nickel and other tiny, uniform metal crystals have novel chemical and physical properties.

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'Smart' sunglasses feature lenses that change color on demand
Chemists at the University of Washington in Seattle say they are developing ‘smart’ sunglasses that will allow the wearer to instantly change the color of their lenses to virtually any hue of the rainbow.

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Plastic that degrades in seawater could be boon for cruise industry and others
In the future, a new type of environmentally friendly plastic that degrades in seawater may make it safe and practical to toss plastic waste overboard ...

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Polymers show promise for gene delivery, tissue scaffolds, other biomedical applications - Virginia Tech polymer scientists have developed a new family of gene vectors – novel polymers that can ferry genetic material across the cell membrane so that it can be incorporated into the machinery of the cell.

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For clean air
Porous manganese oxide garnished with gold nanoparticles removes volatile organic compounds from air and breaks them down.

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New chemistry approach promises less expensive drugs
Enantioselective Organocatalysis using SOMO Activation.

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Technique creates metal memory and could lead to vanishing dents
Plastic Deformation Recovery in Freestanding Nanocrystalline Aluminum and Gold Thin Films.

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MIT biologists solve vitamin puzzle

Solving a mystery that has puzzled scientists for decades, MIT and Harvard researchers have discovered the final piece of the synthesis pathway of vitamin B12 - the only vitamin synthesized exclusively by microorganisms.

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Iron oxide nanoparticles

 
Widely used iron nanoparticles exhibit toxic effects on neuronal cells

Researchers at UC San Diego have discovered that iron-containing nanoparticles being tested for use in several biomedical applications can be toxic to nerve cells and interfere with the formation of their signal-transmitting extensions ...

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Scientists unlock physical, chemical secrets of plutonium
New theory may someday help scientists create safer, more versatile nuclear materials.

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Greenhouse gas effect consistent over 420 million years
New calculations show that sensitivity of Earth's climate to changes in the greenhouse gas carbon dioxide (CO2) has been consistent for the last 420 million years.

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New developments in 'artificial photosynthesis'
Inspired by nature, scientists explore pathways to clean, renewable solar fuel.

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Smart thin film membranes adopt properties of guest molecules - Researchers announced that they had created a nanostructured membrane that incorporates DNA base pairs in order to impart molecular recognition and binding ability to the synthetic material.

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Gold, copper nanoparticles take center stage in the search for hydrogen production catalysts - X-ray studies are pointing the way to less costly and more efficient catalysts for improving the performance of fuel cells.

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Physicists shine a light, produce startling liquid jet
It is possible to manipulate small quantities of liquid using only the force of light.

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Natural mechanism for immune suppression paves way for cancer trials
A natural mechanism pirated by tumors and HIV to evade the immune response is opening the door to better treatment for these conditions, researchers say.

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2-photon absorbing molecules fabricate polymer features just 65 nanometers wide

Producing three-dimensional polymer line structures as small as 65 nanometers wide just became easier with new two-photon absorbing molecules that are sensitive to laser light at short wavelengths, allowing researchers to create them without highly sophisticated fabrication methods.

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Researchers find a new way to read nanoscale vibrations

Nanomechanical oscillators - tiny strips of vibrating silicon only a few hundred atoms thick - are the subject of extensive study by nanotechnology researchers. They could someday replace bulky quartz crystals in electronic circuits or be used to detect and identify bacteria and viruses ...

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Marbles tower shows conflict between oil and water 
How do oil and water really respond to each other?

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Laying microscale tiles
Microcrystalline monolayers: Laying by hand is superior to self-assembly methods.

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Chemists strike gold with new gold catalysts
Gold catalysts are 'hot' because their electrons are heavy, UC Berkeley chemist proposes.

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Study shows metabolic strategy of stressed cell
Major St. Jude study of changes in gene activity and metabolic enzymes show how cells respond to a sudden decrease in the levels of Coenzyme A, a key player in the daily biochemical routines that support life.

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Fingerprinting the Milky Way
Chemical composition of stars in clusters can tell history of our galaxy.

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University of the Basque Country team succeed in characterizing boron nitride on a nanometric scale - A team has completed the first comprehensive study of the properties of boron nitrite on a nanometric scale.

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Snail slime substitutes
A team of engineers have set a small robot climbing walls in order to compare how natural and artificial snail slimes work.

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Mechanics meets chemistry in new way to manipulate matter
The inventors of self-healing plastic have come up with another invention: a new way of doing chemistry.

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Synthetic production of potential pharmaceuticals dramatically simplified by Scripps research team
Findings could expand interest in natural products by making production more cost-effective.

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Powerful new tool to track carbon dioxide by source
Scientists from NOAA’s Earth System Research Laboratory announced a new tool to monitor changes in atmospheric carbon dioxide and other greenhouse gases by region and source.

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American Chemical Society, Portico sign agreement for permanent electronic archiving of ACS content

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UCLA scientists create microscopic alphabet
Research could lead to tiny devices.

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Fullerenes Store Hydrogen
Researchers believe that absorbing properties of fullerenes and other nanostructures that include fullerenes have not been fully investigated ...

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NJIT professor obtains patent to uncover trace elements of airborne pollutants
A breakthrough patent will enable manufacturers to create a device to uncover miniscule amounts of airborne pollutants.

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New sensor detects gaseous chemical weapon surrogates in 45 seconds
Using lasers and tuning forks, researchers have developed a chemical weapon agent sensing technique ...

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New synthetic self-assembling macromolecules mimic nature
Aggregation of Rod-Coil Block Copolymers Containing Rigid Polyampholyte Blocks in Aqueous Solution.

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New JILA apparatus measures fast nanoscale motions
A new nanoscale apparatus developed at JILA offers the potential for a 500-fold increase in the speed of scanning tunneling microscopes (STM) ...

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1-nanometer resolution is NSF CAREER researcher's goal for optical imaging
Producing optical images at resolutions as low as one nanometer is the goal of Virginia Tech College of Engineering researcher Yong Xu ...

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Harvard chemist wins national award for lifetime achievements in chemistry
2007 Priestley Award winner: Harvard Chemist George M. Whitesides, Ph.D.

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How Green are Ionic Liquids?
New international journal CLEAN covers all aspects of sustainability and environmental safety.

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Hidden fingerprints revealed
Hidden fingerprints can be now be revealed quickly and reliably thanks to two developments in nanotechnology.

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Ice created in nanoseconds by Sandia's Z machine
Not expected at your local 7-Eleven anytime soon.

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New reagent delivers a chemical breakthrough at FSU
A newly developed substance could make the jobs of scientists throughout the world a little easier as they work to develop new drugs and other chemicals that benefit humanity ...

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Researchers create artificial enzyme that mimics the body's internal engine
To help scientists achieve a better understanding of how CcO works, researchers have built a new model of the enzyme's active site-a region on the protein's surface where chemical reactions occur.

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RNA enzyme structure offers a glimpse into the origins of life
Researchers have determined the three-dimensional structure of an RNA enzyme, or "ribozyme," that carries out a fundamental reaction required to make new RNA molecules.

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New biofuels process promises to meet all U.S. transportation needs
Purdue University chemical engineers have proposed a new environmentally friendly process for producing liquid fuels from plant matter.

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Chromium 6: A killer compound with an improbable trigger
Even miniscule amounts of chromium 6 can cause cancer. Blame that do-gooder nutrient, vitamin C.

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Phthalates now linked to fat, related health risks
Rochester study connects common chemicals to rising obesity rates.

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No Carrier Necessary: This Drug Delivers Itself
Researchers have describe for the first time a drug delivery system that consists of nanocrystals of a hydrophobic drug.

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Physicists wipe away complexity for a clearer view of heavy nuclei
Coupled-Cluster and Configuration-Interaction Calculations for Heavy Nuclei.

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Physicists tailor magnetic pairings in nanoscale semiconductors
Observation of the two-channel Kondo effect: by applying voltages to nanoscale electrodes, scientists can tune how strongly a magnetic atom couples to one set of electrons, or channel, compared to the other set ...

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First ozone and nitrogen dioxide measurements from MetOp-A
The Global Ozone Monitoring Experiment-2 (GOME-2) on board MetOp-A launched in October 2006 and currently undergoing commissioning has delivered the first geophysical products for monitoring the Earth's ozone layer, and European and global air quality.

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First new waterborne aquaculture drug in 20 years approved
Twelve years of rigorous research by USGS scientists helped lead to the approval by the Food and Drug Administration (FDA) of the first waterborne drug for fish diseases in more than 20 years.

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Progress toward artificial photosynthesis?
Direct activation with graphitic carbon nitride makes carbon dioxide accessible for chemical synthesis.

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Rings made of little rods
Water droplets as templates - Gold nanorods self-assemble into rings.
Gold nanorods assemble themselves into rings
Finding by Rice University chemists could aid development of new nanodevices.

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Color analysis rapidly predicts carbon content of soil
Scientists report in the Soil Science Society of America Journal that soil color can be as accurate as the lab for carbon content.

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A single-photon server with just one atom
Physicists at Max Planck Institute of Quantum Optics have succeeded in turning a Rubidium atom into a single-photon server.

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Studies force new view on biology of flavonoids
Flavonoids, a group of compounds found in fruits and vegetables that had been thought to be nutritionally important for their antioxidant activity, actually have little or no value in that role, according to an analysis by scientists in the Linus Pauling Institute at Oregon State University.

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Secret of worm's poison pill box protein could produce new natural insecticide
Researchers have discovered how a protein from a bacterium acts like a cunningly designed poison pill box that could now be used as a basis of a new range of natural insecticides.

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A sensor created from a microporous silicon structure

Diatom conversion

Microscopic sea creatures provide foundation for gas sensors and other devices.

The three-dimensional shells of tiny ocean creatures could provide the foundation for novel electronic devices, including gas sensors able to detect pollution faster and more efficiently than conventional devices.

Using a chemical process that converts the shells’ original silica (silicon dioxide, SiO2) into the semiconductor material silicon, researchers have created a new class of gas sensors based on the unique and intricate three-dimensional (3-D) shells produced by microscopic creatures known as diatoms.

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Super small nanoelectrodes can probe microscale environments
Investigating the composition and behavior of microscale environments, including those within living cells, could become easier and more precise with nanoelectrodes being developed at the University of Illinois.

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Scientists uncover link between ocean's chemical processes and microscopic floating plants - Research sheds light on how these processes regulate climate.

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Regardless of global warming, rising CO2 levels threaten marine life
Like a piece of chalk dissolving in vinegar, marine life with hard shells is in danger of being dissolved by increasing acidity in the oceans.

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MIT particles pave way for new bedside diagnostics
Researchers have created an inexpensive method to screen for millions of different biomolecules (DNA, proteins, etc.) in a single sample-a technology that could make possible the development of low-cost clinical bedside diagnostics.

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Protein sciences - A novel assay allows simultaneous detection of individual proteins and their interactions in living cells.

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Carbon dioxide and the ocean
A new scientific paper quantifies over a half-century of environmental research.

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Unlocking the secrets of high-temperature superconductors
Understanding the mechanism of superconductivity may one day help scientists design superconductors able to function closer to room temperature for applications such as more-efficient power transmission.

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Atoms under the mantle

At a depth of 2900 kilometres, the layer between the Earth's mantle and its core has always intrigued geophysicists because they are unable to explain the seismic data it generates. Researchers have studied its deformation which influences convection movements within the mantle or even those by tectonic plates ...

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Model of a graphene membrane

 

Invisible for Electrons
Scientists fabricate ultra-thin membranes.

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Fluorescent antifreeze proteins

Fluorescence microscopy reveals why some antifreeze proteins inhibit ice growth better than others

Finding could have medical, commercial applications.

Antifreeze or “ice structuring” proteins – found in some fish, insects, plants, fungi and bacteria – attach to the surface of ice crystals to inhibit their growth and keep the host organism from freezing to death. Scientists have been puzzled, however, about why some ice structuring proteins, such as those found in the spruce budworm, are more active than others.

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New success in engineering plant oils
Technique could yield materials to replace petrochemicals and more nutritious edible oils.

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New nanoscale engineering breakthrough points to hydrogen-powered vehicles
Researchers have developed an advanced concept in nanoscale catalyst engineering – a combination of experiments and simulations that will bring polymer electrolyte membrane fuel cells for hydrogen-powered vehicles closer to massive commercialization.

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Imaging 'gridlock' in high-temperature superconductors
Superconductivity - the conduction of electricity with zero resistance - sometimes can, it seems, become stalled by a form of electronic "gridlock" ...

•

Super-fermenting fungus genome sequenced
To be harnessed for improved biofuels production.

 

ACS News:

•

The first urine test to detect insulin doping in athletes

Scientists in Germany are reporting development of a urine test that finally can identify athletes who misuse certain kinds of insulin in an illicit attempt to enhance performance.

Mario Thevis and colleagues say that amateur and elite athletes reportedly have used long-acting, as well as rapid-acting, forms of insulin to gain an edge - although insulin doping’s actual ability to enhance performance remains uncertain.

Their article, scheduled for the April 1 edition of ACS’ Analytical Chemistry, a semi-monthly journal, states that scientists had not attempted to develop such a test in the past because of the presumption that it was impossible to detect insulin’s degradation products, the compounds formed as the body breaks down insulin.

Using urine samples from volunteers, including athletes with diabetes, the scientists were able to identify degradation products from Lantus insulin, one commonly used form of insulin. The test could not identify surreptitious use of two other forms of long-duration insulin, but the study uncovered clues that toward that goal. “Determination of long-acting insulin analogues in urine is of utmost interest for doping control purposes,” the study notes. “The developed and validated procedure provides a fast and reliable way to elucidate the potential misuse of the long-acting insulin analogue LAN in regular doping control specimens.”

Analytical Chemistry: “Mass Spectrometric Identification of Degradation Products of Insulin and Its Long-Acting Analogues in Human Urine for Doping Control Purposes” - [ pdf text ]

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Vegetable soup chemical reactions

Chemists working on tight budgets in developing countries may be able to substitute extracts of potatoes, celery, eggplant, carrot, cassava, horseradish or an array of inexpensive and locally available vegetable products for the costly reagents traditionally needed for chemical reactions, a new study suggests.

In a review scheduled for the March 23 issue of the ACS’ Journal of Natural Products, a monthly publication, Geoffrey A. Cordell at the University of Illinois at Chicago and colleagues in Brazil explain that the high cost of imported reagents - substances used in chemical reactions - is a major problem for such academic, chemical industry and pharmaceutical laboratories in developing countries. Their report describes how some of the more than 7,000 vegetable crops grown throughout the world can be used as substitutes for commercial reagents in laboratory work.

“The evaluation of locally available vegetables, fruits, common plants, and natural waste products for a selection of standard organic chemical reactions of commercial significance could prove to be a very valuable economic endeavor,” the report notes. “It may well offer new opportunities to expand the role of natural products as sustainable chemical reagents where high-cost, nonrenewable reagents are presently used.”

Natural Products: “Vegetables as Chemical Reagents” - [ pdf text ]

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Elevated arsenic levels reported in rice grown in South Central States

The largest market basket survey of the arsenic content of rice grown in the United States has found elevated levels of arsenic in rice produced in the South Central part of the country, scientists report in an article scheduled for the April 1 issue of ACS’ Environmental Science & Technology, a semi-monthly journal. The University of Aberdeen’s A. A. Meharg and colleagues did the study, which involved analyses of rice purchased at U. S. supermarkets. A previous study found that U. S. rice purchased in the United Kingdom had higher arsenic levels than rice grown in Europe, India or Bangladesh.

In the study, researchers compared arsenic levels in rice from the two main rice-producing areas of the country - the South Central States and California. They focused on inorganic arsenic, which the report describes as a known human carcinogen and implicated in several other diseases. Rice grown in the South Central States had more arsenic than California rice. Rice in those states often is grown in old cotton fields that previously were treated with arsenic pesticides, the study states, adding that arsenic-tolerant strains of rice often are grown in those fields.

When researchers modeled rice intake, they concluded that certain population groups could get dietary exposure to arsenic that exceeds California’s state exposure limits. Those groups include low-income individuals who consume large amounts or rice as an inexpensive food; people with celiac disease (who eat rice as part of a gluten-free diet); Asian-Americans who consume a high-rice diet; and Hispanic infants and toddlers, who also have a diet high in rice, the study notes.

Environmental Science & Technology: “Market Basket Survey Shows Elevated Levels of As in South Central U. S. Processed Rice Compared to California: Consequences for Human Dietary Exposure” - [ pdf text ]

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Red pepper: Hot stuff for fighting fat?

Food scientists in Taiwan are reporting new evidence from laboratory experiments that capsaicin - the natural compound that gives red pepper that spicy hot kick - can reduce the growth of fat cells. The study is scheduled for the March 21 issue of the ACS’ Journal of Agricultural and Food Chemistry, a bi-weekly publication.

In the report, Gow-Chin Yen and Chin-Lin Hsu cite previous research suggesting that obesity can be reduced by preventing immature fat cells (adipocytes) from developing into mature cells. Past research also linked capsaicin to a decrease in the amount of fat tissue and decreased blood-fat levels. With that knowledge, the researchers tested capsaicin’s effects on pre-adipocytes and adipocytes growing in laboratory cultures.

They found that capsaicin prevented pre-adipocytes from filling with fat and becoming full-fledged fat cells. The effects occurred at levels just slightly greater than those found in the stomach fluid of an individual eating a typical Indian or Thai diet, the researchers noted. Capsaicin worked by providing a biochemical signal that made fat cells undergo apoptosis, a mechanism in which cells self-destruct.

Journal of Agricultural and Food Chemistry: “Effects of Capsaicin on Induction of Apoptosis and Inhibition of Adipogenesis in 3T3-L1 Cells” - [ pdf text ]

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The Chemistry of the Holy Land

Chemical research is thriving in Israel - a tiny country far away from major scientific centers and surrounded by hostile neighbors. The country ranks third in the world in research papers published per million population. That’s just one characteristic detailed in the profile of science in the Holy Land based on visits to 30 research groups by Chemical & Engineering News, ACS’ weekly newsmagazine.

“The odds of developing a successful chemical research program in such a place and under such circumstances might seem slim, and the task may seem daunting,” reports C&EN senior editor Mitch Jacoby, who wrote the cover story. “Yet Israeli chemists don’t seem particularly fazed by the challenge. ‘Kacha zen ba’arets,’ they say in a matter-of-fact way - “That’s just the way things are in Israel.”

In the article, Jacoby draws on interviews with scientists at institutions throughout Israel to provide a sweeping view of the kinds of research projects underway in Israel, and the scientific life in the Holy Land. The article draws contrasts with science in the West, noting, for instance that young Israeli scientists begin their careers older, due to mandatory military service, and work in a culture of usually-small research groups and modest budgets.

Chemical & Engineering News: “Chemistry in the Holy Land: Political turmoil - not research topics - distinguishes Israel from the West”

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Physicists reveal water's secrets in journal 'Science'
It's essential to all life, and numerous research papers are published about it every year. Yet there are still secrets to reveal about water, that seemingly simple compound we know as H2O.

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Computer-designed molecule to clean up fluorocarbons?
In a powerful demonstration of the relatively new field of computational chemistry, researchers have designed a wholly theoretical molecule to pull the fluorine out of fluorocarbons.

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Natural antibiotics yield secrets to atom-level imaging technique
Frog skin and human lungs hold secrets to developing new antibiotics, and a technique called solid-state NMR spectroscopy is a key to unlocking those secrets.

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Genome sequencing reveals key to viable ethanol production
As the national push for alternative energy sources heats up, researchers have for the first time identified how genes responsible for biomass breakdown are turned on in a microorganism that produces valuable ethanol from materials like grass and cornstalks.

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Quantum effects make the difference
A team of German and American researchers observe a new phase transition at absolute zero.

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Delicate relation between single spins
Scientists measure the magnetic interaction between single atoms.

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Sphingolipids with therapeutic ends
Sphingolipids operate in the cells and they can regulate certain biological functions.

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Wanted: Research work in chemoinformatics by young scientists
German-American prize "CINF Scholarship for Scientific Excellence" is designed to reward outstanding research of young scientists and to foster their contribution to chemical information.

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Monochloramine treatment not as effective in protecting drinking water

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New book brings chemistry to life with art, history, humor
A new book by a University of New Hampshire professor chronicles the beauty, mystery, truths, lies, and even humor of chemistry.

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Dubbed 'nano-piezotronics'
Researchers create new class of electronic components by bending zinc oxide nanowires.

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Fats into jet fuel - NC State 'green' technology licensed
New biofuels technology has the potential to turn virtually any fat source – vegetable oils, oils from animal fat and even oils from algae – into fuel to power jet airplanes.



February 2007


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New insights into high-temperature superconductors
Scientists have discovered that two different physical parameters - pressure and the substitution of different isotopes of oxygen (isotopes are different forms of an element) - have a similar effect on electronic properties of mysterious materials called high-temperature superconductors.

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Study of atomic movement may influence design of pharmaceuticals
Chemists at the University of Liverpool have designed a unique structure to capture the movement of atoms which may impact on future designs of pharmaceuticals.

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Ingredient in Big Macs and sodas can stabilize
Gold nanoparticles could be used to detect and treat cancer and other diseases.

 

ACS News:

•

Coffee: Aroma, taste and dietary fiber

Already recognized as a source of healthful anti-inflammatory and antioxidant compounds, coffee also contains significantly higher levels of soluble dietary fiber than other commonly consumed beverages, scientists in Spain report. Their study is scheduled for publication in the March 21 issue of ACS' Journal of Agricultural and Food Chemistry, a biweekly journal.

Fulgencio Saura-Calixto and M. Elena Diaz-Rubio point out that coffee is a complex chemical mixture that reportedly contains more than 1,000 different compounds, some of which have been linked to good and bad effects on human health. Scientists have known that coffee beans are rich in soluble dietary fiber (SDF) that can pass into brewed coffee, the researchers added, noting, however, that little research has been done on the topic.

In the new study, researchers used a special technique for measuring dietary fiber in beverages to show that brewed coffee contains a significant amount of SDF — 02.5 percent to 20.0 percent by weight of powdered coffee bean. "The dietary fiber content in brewed coffee is higher than in other common beverages such as wine or orange juice," the study states.

The findings mean that consumption of 1 cup (about 200 milliliters) of coffee per day represents a contribution of up to 1.8 grams of the recommended intake of 20-38 grams of this essential nutrient, the researchers noted.

Journal of Agricultural and Food Chemistry: "Dietary Fiber in Brewed Coffee"

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Toward tapping the potential of "stranded" natural gas

Newly discovered chemical catalysts may be an answer to the century-long search for economical ways of using natural gas now burned or "flared" as waste in huge quantities, scientists in the United States and Germany report. Their study is scheduled for the March 7 issue of the Journal of the American Chemical Society, a weekly publication.

Johannes A. Lercher and colleagues at the Technical University of Munich and Dow Chemical Company explain that 30 percent to 60 percent of the world's natural gas is classified as "stranded," meaning that it cannot be used locally or transported economically to other markets. When produced in the course of pumping crude oil, such gas is vented to the atmosphere or burned at the wellhead.

That wasted natural gas is mainly methane, a compound in great demand as a chemical feedstock, a basic raw material for making chemicals that are subsequently used to make hundreds of medical, commercial and industrial products. No practical technology has been available, however, for using the methane in natural gas as a chemical feedstock. The new study describes research on lanthanum-based catalysts that convert methane into a compound that would be an ideal chemical feedstock.

Journal of the American Chemical Society: "Methyl Chloride Production from Methane over Lanthanum-Based Catalysts"

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Transforming "yellow grease" into therapeutic cosmetics

Waste cooking oil from restaurant deep fryers could become a much-sought inexpensive raw material for producing unusual biosurfactants with uses ranging from therapeutic cosmetics that regenerate damaged skin to controlling algae blooms in lakes and ponds, according to researchers in New York.

In a report scheduled for the April 9 issue of the ACS bimonthly journal Biotechnology Progress, Vishal Shah and colleagues estimate that restaurants in the United States generate about 25 billion gallons of waste cooking oil each week. The waste oil, marketed as "yellow grease," long has been used in animal feed, with researchers exploring new applications such as biodiesel fuel.

"We have successfully demonstrated the use of restaurant waste oil as a potential low-cost lipid feedstock for sophorolipid production," the report states. "This method of waste oil disposal has the advantage of producing a value-added commercially viable byproduct." Sophorolipids have a range of applications, including naturally derived ingredients in therapeutic cosmetics; germicidal solutions for washing fruits and vegetables; and anti-algal agents for environmental cleanups, the report notes.

Biotechnology Progress: "Utilization of Restaurant Waste Oil as a Precursor for Sophorolipid Production"

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Toward powerful new anticancer drugs with new ways of targeting tumors

The search for new anticancer drugs has led scientists in Pittsburgh to synthesize a compound that works in a different way than existing agents and is so potent that minute levels of 10 parts per trillion block the growth of tumor cells in laboratory experiments. Kazunori Koide and colleagues describe the compound as one of the most potent of all anticancer agents in a report scheduled for the March 7 issue of the Journal of the American Chemical Society.

The parent compound, FR901464, inhibited the growth of cancer cells implanted into laboratory mice. Because of structural similarity between FR901464 and their analogue, called meayamycin, the Koide group is cautiously optimistic that meayamycin also will be effective against tumors in mice. The amount that the Koide employed against cancer cells is equivalent to 10 seconds in 32,000 years or one packet of sugar (5 grams) in a coffee cup the size of 400 Olympic-size pools.

In the article, researchers explain that existing chemotherapy medications work by targeting only a handful of vulnerable spots in a tumor, such as the DNA or hormone receptors. That limited range of targets has led scientists to seek new generations of medications that work in different ways.

Journal of the American Chemical Society: "Total Synthesis, Fragmentation Studies, and Antitumor/Antiproliferative Activities of FR901464 and Its Low Picomolar Analogue"

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A new target in the war on cancer

A new family of potential anti-cancer drugs is quietly causing excitement in the pharmaceutical industry as early data from clinical trials shows promising responses in patients, according to an article scheduled for the Feb. 26 issue of Chemical & Engineering News (C&EN), the ACS' weekly newsmagazine.

In the article, C&EN associate editor Lisa Jarvis explains that the new compounds may circumvent the long-standing problem of drug resistance, in which anti-cancer drugs gradually loose their effectiveness. The drugs focus on a new target in the war against cancer — a substance called heat shock protein 90 (Hsp90). Heat shock proteins are most active when the cell is exposed to elevated temperatures, infection, inflammation, toxins and other stresses that can cause a protein to unfold. Like housekeepers, heat shock proteins help those proteins — including mutated, cancer-causing proteins — get back into their proper shape.

When Hsp90's effects are blocked in cancer cells, those cancer-causing proteins cannot survive, potentially stopping the disease in its track. When Hsp90's effects are blocked in cancer cells, damaged proteins accumulate, and the cell dies. Jarvis explains that cancer cells, with their horribly mutated proteins, seem to be especially dependent on Hsp90, and more vulnerable than other body cells when Hsp90's effects are blocked. The article describes how new discoveries have changed heat shock proteins from laboratory curiosities into some of today's most promising targets for developing new drugs.

Chemical & Engineering News: "Living on the Edge: Drugs targeting Hsp90 push already unstable cancer cells to the brink"

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A propane liquid nanobridge breaks up in a vacuum.

Fluid dynamics works on nanoscale in real world

Scientists show theory works outside of a vacuum.

It's well-known that small systems are influenced by randomness and noise more than large systems. Because of this, Georgia Tech physicist Uzi Landman reasoned that modifying the Navier-Stokes equations to include stochastic elements – that is give the probability that an event will occur – would allow them to accurately describe the behavior of liquids in the nanoscale regime ...

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Peanut-shaped nanostructures
Anisotropic palladium sulfide–cobalt sulfide–palladium sulfide nanoparticles.

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Lower carbon dioxide emissions from coal-fueled power plants possible with technology development
A more economical technology for a 90 percent reduction of carbon dioxide emissions from coal-fueled power plants is being developed by a chemical engineer and his colleagues at The University of Texas at Austin as part of the TXU Carbon Management Program.

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New stamping process creates metallic interconnects, nanostructures
Researchers have developed a simple and robust electrochemical process for the direct patterning of metallic interconnects and other nanostructure.

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In presence of fragrant cleaning products, air purifiers that emit ozone can dirty the air - Results of study may help California officials regulate indoor air purifiers.

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The mysterious case of Columbus's silver ore
Silver-bearing ore found at the settlement founded by Christopher Columbus's second expedition was not mined in the Americas, new research reveals.

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Under pressure, vanadium won't turn down the volume
Scientists have discovered a new type of phase transition - a change from one form to another - in vanadium, a metal that is commonly added to steel to make it harder and more durable.

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The connector rotation hypothesis?
Phage do not pack their DNA by rotation.

 

ACS News:

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Cells may contain hundreds of thousands to millions of ribosomes, one of which is depicted in this image.

Journal of the American Chemical Society:

Sonochemical Synthesis of Nanosized Hollow Hematite

A new process for making much-sought iron nanospheres

Using a process that creates bubbles as hot as the surface of the sun, chemists are reporting development of a new method for making hollow hematite (iron oxide) nanospheres. The University of Illinois at Urbana-Champaign's Kenneth S. Suslick and Jin Ho Bang describe the synthesis of these iron nanoparticles in a report scheduled for the Feb. 28 issue of the Journal of the American Chemical Society, a weekly publication.

Hollow nanospheres of metals and other inorganic materials are generating great interest because of their unusual properties and potential applications in drug delivery, electronic components, catalysts and other products. "We believe that this procedure will be easily extended to prepare other hollow inorganic materials," the researchers note. In the past, production of hollow hematite nanospheres required a time-consuming process and use of toxic hydrofluoric acid.

The new process uses sonochemistry, in which high-frequency sound waves are focused into a solution containing an iron compound and carbon nanoparticles. Those sound waves create tiny bubbles in the liquid. The collapse of those bubbles causes intense local heating with temperatures estimated at 9,000 F, which is nearly as hot as the surface of the sun. The sonochemical process forms iron spheres around the carbon nanoparticles. On exposure to air, the iron rapidly oxidizes, which burns away the carbon core, leaving hematite spheres one thousandth the diameter of a red blood cell.

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Recipe for healthy garlic: Crush before cooking

"Stop and smell the garlic - that's all you have to do," advised William Shatner, whose starring roles ranged from Captain Kirk in Star Trek to himself in Iron Chef USA. New scientific research is editing Shatner's advice for the millions of people seeking garlic's fabulous flavor and its reputed health benefits. Make it read: Stop and crush the garlic.

Claudio R. Galmarini and colleagues in Argentina and the United States are reporting new evidence that crushing garlic before cooking can reduce the loss of garlic's healthful properties. In a report scheduled for the March 7 edition of ACS' Journal of Agricultural and Food Chemistry, a bi-weekly publication, they note that many past studies of garlic and health used raw garlic. The new study joins a handful or others to examine how the heat of cooking affects the chemical compounds associated with garlic's beneficial health effects.

The researchers found that even a few minutes of cooking reduces levels of those compounds. The reduction is steepest in whole garlic, and less pronounced in garlic that has been crushed before cooking. Crushing or chopping garlic releases an enzyme, alliinase, that catalyzes the formation of allicin, which then breaks down to form a variety of healthful organosulfur compounds. The researchers believe that crushing garlic before cooking may allow alliinase to work before cooking inactivates the enzyme. Their report notes that allowing crushed garlic to stand for 10 minutes before cooking may further enhance formation of those compounds before heat inactivates alliinase.

Journal of Agricultural and Food Chemistry: "Effect of Cooking on Garlic (Allium sativum L.) Antiplatelet Activity and Thiosulfinates Content"

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New e-waste recycling technology

With megatons of obsolete personal computers, old cell phones and other waste electrical and electronic equipment piling up every year, scientists in China report development of a much-needed new recycling and recovery technology for one of the most troublesome components of e-waste - printed circuit boards (PCBs).

In a report scheduled for the Feb. 15 edition of ACS' Environmental Science & Technology, a semi-monthly journal, Zhenming Xu and colleagues point out that PCBs are an ideal target for recycling and reuse. PCBs are self-contained modules of interconnected electronic components formed by a thin layer of conducting material deposited, or "printed," on the surface of an insulating board. They contain materials potentially toxic if released to the environment. However, PCBs also are a rich potential source of valuable metals and other materials that could be recovered and reused.

The researchers describe tests of their process on almost a half-ton of scrap PCBs, which showed that it is efficient and environmentally friendly. The technology involves special crushing of scrap PCBs, followed by separation of the metallic and non-metallic materials with an electric field. The technique has advantages over other methods proposed for recycling PCBs, the researchers indicate.

Environmental Science & Technology: "Recycle Technology for Recovering Resources and Products from Waste Printed Circuit Boards"

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Storing Digital Data in Living Organisms

DNA, perhaps the oldest data storage medium, could become the newest as scientists report progress toward using DNA to store text, images, music and other digital data inside the genomes of living organisms. In a report scheduled for the April 9 issue of ACS' Biotechnology Progress, a bi-monthly journal, Masaru Tomita and colleagues in Japan point out that DNA has been attracting attention as perhaps the ultimate in permanent data storage.

Data encoded in an organism's DNA, and inherited by each new generation, could be safely archived for hundreds of thousands of years, the researchers state. In contrast, CD-ROMs, flash memory and hard disk drives can easily fall victim to accidents or natural disasters.

In their report, the researchers describe a method for copying and pasting data, encoded as artificial DNA, into the genome of Bacillus subtilis, (B. subtilis) a common soil bacterium, "thus acquiring versatile data storage and the robustness of data inheritance." The researchers demonstrated the method by using a strain of B. subtilis to store the message: "E=MC2 1905!" — Albert Einstein's famous 1905 energy-mass equivalence equation.

"We suggest that this simple, flexible and robust method offers a practical solution to data storage and retrieval challenges in combination with other, previously published techniques," the report states.

Biotechnology Progress: "Alignment-Based Approach for Durable Data Storage into Living Organisms"

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'Watching atoms move' is goal of powerful new X-ray sources
A new generation of X-ray sources is allowing scientists to watch atoms move.

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Physics graduate student creates graphene resonator
A single sheet of graphene, a form of carbon atoms in a plane just one atom thick, can be isolated and used as an electromechanical resonator.

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High-quality helium crystals show supersolid behavior
High-quality, single-crystal, ultra-cold solid helium exhibits supersolid behavior, suggesting that this frictionless solid flow is not a consequence of defects and grain boundaries in poor-quality, polycrystalline, solid helium, according to a team of Penn State researchers.

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Isotope science to have wide-ranging impact, NSCL researcher says
Nuclear science - and a host of other endeavors that involve the production, study and use of rare isotopes - is undergoing a quiet but dramatic revolution.

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UI researcher cites need for a 'small view' of the environment
By thinking small, scientists can solve big environmental problems.

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Green chemistry can help nanotechnology mature, Oregon professor says
Planning now can reduce risks of environmental and health-related side effects.

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Disorder may be in order for 'spintronic' devices
Physicists are using ultrashort pulses of laser light to reveal precisely why some electrons, like ballet dancers, hold their spin positions better than others ...

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Strain has major effect on high-temp superconductors
Just a little mechanical strain can cause a large drop in the maximum current carried by high-temperature superconductors, according to novel measurements carried out by NIST ...

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It's not easy being green
Ethanol production requires careful management for maximum environmental benefits.

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Cellulosic ethanol: Fuel of the future?

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Successful development of prototype assays
International medical diagnostics company Panbio Limited today announced that it had developed two prototype immunoassays using their proprietary panDA Homogeneous Assay technology.

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Research confirms Renaissance painting
Scientific analyses of paint from a Madonna and Child painting have supported the attribution of the work to the Renaissance period.

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Scientists use nanoparticle to discover disease-causing proteins
A complex molecule and snake venom may provide researchers with a more reliable method of diagnosing human diseases and developing new drugs.

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Changing gold
Gold is more unstable than thought ...

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Psychologist explains the neurochemistry behind romance
The Beatles' George Harrison wondered in his famous love song about the "something" that "attracts me like no other lover." A University at Buffalo expert explains that that "something" is actually several physical elements that ...

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Instruction Manual for Creating a Molecular Nose

Max Planck researchers incorporate odorant receptors into artificial membranes.

An artificial nose could be a real benefit at times: this kind of biosensor could sniff out poisons, explosives or drugs, for instance. Researchers at the Max Planck Institute for Polymer Research and the Max Planck Institute of Biochemistry recently revealed a technique for integrating membrane proteins into artificial structures. Membrane proteins have several important functions in the cell, one of which is to act as receptors, passing on signals from molecules in the air, for example, to the cell interior ...

 

ACS News:

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The Future of Microbial Cellulose in Biomedical Applications

Biomacromolecules:

"The Future of Microbial Cellulose in Biomedical Applications"

Microbial cellulose: Poised for a high-profile role in biomedicine

Biotechnology's next high-value product could be microbial cellulose, a form of cellulose produced naturally by bacteria that already has found some successful applications in medicine, according to an article in the current issue of ACS' Biomacromolecules, a monthly journal.

In their review of worldwide research on microbial cellulose, the University of Texas' R. Malcolm Brown Jr. and colleagues in Poland explain that it is chemically identical to the more-familiar plant cellulose, source of paper and other commercial products. However, cellulose produced by the bacterium Acetobacter xylinum has a unique nanostructure of fibers that make it ideal as a dressing to speed wound healing and for a range of other biomedical applications.

Microbial cellulose already has been used successfully in patients with severe burns, for instance, and as a replacement for small-diameter blood vessels, the scientists point out. Based on the review, they conclude that microbial cellulose is poised for use in a wide variety of medical devices and consumer products as soon as scientists develop a method to mass produce the material.

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Protein Microstructures

Journal of the American Chemical Society:

"Mask-Directed Multiphoton Lithography"

A rapid new process for fabricating microstructures from protein

In an advance in microfabrication technology, scientists report development of a new method for rapidly engineering complex micro-scale patterns and three-dimensional microstructures from biocompatible protein.

Jason B. Shear and Bryan Kaehr describe using the laser technique to fabricate detailed shapes — such as the silhouette of a housefly and the State of Texas — by condensing (or crosslinking) proteins in solution into a solid matrix. Their study is scheduled for the Feb. 28 issue of the Journal of the American Chemical Society, a weekly publication. The researchers also used the process to fabricate minute 3-D structures, including 1- and 2-story microcontainers that were used to trap, incubate and grow as few as a single living bacterium into colonies. Such traps could have a variety of uses, including studying the formation of biofilms, which are the source of human health concerns.

The technique, mask-directed multiphoton lithography, is modeled after the photolithography processes widely used to transfer electronic circuits onto a semiconductor wafer by projecting light through a pattern or "mask." However, the new method uses a special laser to scan objects or patterns printed on transparency film with an ordinary desktop printer. The silhouette ultimately is refocused into the protein solution using the objective lens of a microscope. Because protein molecules must be extremely close to the laser focus to undergo crosslinking into solid material, this method allows structures to be created with complex 3-D shapes. The process takes only minutes, researchers report.

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New potential health benefit of olive oil for peptic ulcer disease

Already fabled for an array of health benefits, extra virgin olive oil — a centerpiece of the Mediterranean Diet — may have a new role in helping to prevent and treat Helicobacter pylori (H. pylori) infections, which cause millions of cases of gastritis and peptic ulcer disease each year, researchers in Spain report.

Manuel Brenes and colleagues cite past studies showing that green tea, cranberry juice and certain other natural foods inhibit the growth of H. pylori (which infects the stomach lining), leading researchers to recommend consumption of those foods. None of the numerous studies on olive oil, however, has tested its effects on H. pylori, they note in a study scheduled for the Feb. 21 issue of ACS' Journal of Agricultural and Food Chemistry, a biweekly publication.

Brenes and colleagues used laboratory experiments to demonstrate that under simulated conditions the healthful phenolic compounds in extra virgin olive oil remain stable in the acidic environment of the stomach for hours. In laboratory cultures, those substances had a strong antibacterial effect against eight strains of H. pylori, including antibiotic-resistant strains.

"These results open the possibility of considering extra virgin olive oil a chemoprotective agent for peptic ulcer or gastric cancer, but this bioactivity must be confirmed in vivo in the future," they conclude.

Journal of Agricultural and Food Chemistry: "In Vitro Activity of Olive Oil Polyphenolic against Helicobacter pylori".

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Toward a three-in-one airport passenger and baggage security scanner

Scientists in California and Michigan report development toward a "universal point detection system," a long sought three-in-one machine that screens airline passengers and baggage for explosive, chemical and biological threats at the same time. George R. Farquar and colleagues describe latest tests on the device, which uses a technology called single-particle aerosol mass spectrometry (SPAMS), in an article scheduled for the March 15 issue of the ACS' Analytical Chemistry, a semi-monthly journal.

In previous research, the scientists developed and tested effectiveness of a SPAMS system for the detection of chemical and biological agents. The new research expands SPAMS' capabilities to include several kinds of explosives that have been used worldwide in improvised explosive devices and other terrorist attacks.

The study concludes that SPAMS has the potential to detect the presence of explosives even if only one dust-speck-sized particle weighing one trillionth of a gram, (one gram is one-twenty-eighth of an ounce), is present on an individual's clothing or baggage. "SPAMS is a sensitive, specific, reliable option for airport and baggage screening," the report states. "The ability of the SPAMS system to determine the identity of a single particle is a valuable asset when the target analyte is dangerous in small quantities or has no legal reason for being present in an environment."

Analytical Chemistry: "Identification of High Explosives Using Single-Particle Aerosol Mass Spectrometry".

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Physicists set 'speed limit' for future superconducting magnet
A research team has identified a high-temperature superconductor - Bi-2212 - as a material that might be suitable for the new wires needed to one day build the most powerful superconducting magnet in the world, a 30 Tesla magnet.

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Grape expectations for healthier wine
Hypoallergenic alternative treatment boosts antioxidants in grapes.

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MIT experts foresee efficient ethanol production
Express views via Science commentary, Senate testimony.

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Flowing bubbles mimic computer
Work could boost capabilities of 'labs on a chip'.

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Nanotechnology meets biology and DNA finds its groove
Pity the molecular biologist.

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Shedding new light on proteorhodopsin
New light has been shed on proteorhodopsin, the light-sensitive protein found in many marine bacteria.

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Loss of a universal tRNA feature reported
Scientists report in the Journal of Bacteriology that two alphaproteobacteria lack the universal extra guanylate nucleotide typically found in the transfer RNA molecule tRNAHis ...

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First 2-D Pictures of a 'frequency comb' transform it into a brush
Technique reveals colors and intensity of all lightwaves simultaneously.

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JILA measurements recast usual view of elusive force
Physicists have demonstrated that the warmer a surface is, the stronger its subtle ability to attract nearby atoms, a finding that could affect the design of devices that rely on small-scale interactions, such as atom chips, nanomachines, and microelectromechanical systems.

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Man-made proteins could be more useful than real ones

Researchers have constructed a protein out of amino acids not found in natural proteins, discovering that they can form a complex, stable structure closely resembling a natural protein. Their findings could help scientists design drugs that look and act like real proteins but won't be degraded by enzymes or targeted by the immune system, as natural proteins are.

The researchers, led by Howard Hughes Medical Institute (HHMI) professor Alanna Schepartz, report their findings in the February 14, 2007, issue of the Journal of the American Chemical Society, published in advance online on January 19, 2007...

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Cold storage solution for global warming?
University researchers suggest CO2 be frozen in underground reservoirs.

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Volcanoes and nanotechnology
Etna produces catalyst: Direct synthesis of carbon nanotubes with volcanic rock.

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Navigable nanotransport
Direct synthesis of hollow nanoscopic spheres with tailored surfaces.

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Universe contains more calcium than expected
This conclusion was drawn by astronomers of the SRON Netherlands Institute for Space Research, after observations with ESA's XMM-Newton X-ray observatory.

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Yale chemists show that nature could have used different protein building blocks
Chemists at Yale have done what Mother Nature chose not to - make a protein-like molecule out of non-natural building blocks, according to a report featured early online in the Journal of the American Chemical Society.

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Scientists find why conductance of nanowires vary
Discovery has implications for nanotech development.

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Nanomicroscopy reveals the collective transport of gold atoms in real-time
Researchers used a High Resolution Electron Microscope to observe in real-time the collective transportation of gold atoms in a thin layer.

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MIT 'microsieve' could aid study of diseases
Device promises to speed up separation, sorting of proteins.

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University of Delaware engineers receive grant for energy research
Researchers at the University of Delaware have received a $960,000 grant to identify low-cost, nano-sized catalysts - tiny amounts of metal compounds - that can spur the chemical conversion of liquid fuels into hydrogen for powering cars to heating homes.

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Microprinting technique for patterning single molecules - A new process for creating patterns of individual molecules on a surface combines control of self-assembled monolayers (SAMs) and a soft-lithography technique known as microcontact printing.

 

ACS News:

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Tangerine Tomato

Tangerine Tomato

"Carotenoid Absorption in Humans Consuming Tomato Sauces Obtained from Tangerine or High-beta-Carotene Varieties of Tomatoes"

Journal of Agricultural and Food Chemistry

The tangerine: Top tomato?

Research involving tomato sauce made from an heirloom tomato variety named the tangerine tomato has established that a specific chemical form of lycopene is more effective in increasing the levels of this much-heralded antioxidant in people's blood. Ohio State University's Steven J. Schwartz and colleagues point out that many deeply colored vegetables and fruits are rich in lycopene, a carotenoid linked to health benefits. However, not all of the lycopene is bioavailable - able to be absorbed into the blood after consumption, they note in a report scheduled for the Feb. 7 issue of the ACS' Journal of Agricultural and Food Chemistry, a bi-weekly journal.

Red tomatoes, for instance, are very rich in lycopene, but it is the so-called trans isomer, a chemical form different from the cis isomer, that people absorb more efficiently into the body. In their experiments, researchers fed volunteers tomato sauce made from tangerine tomatoes, which have a bright orange color and more of the cis lycopene isomer. Volunteers also ate tomato sauce made from a different tomato variety especially rich in another carotenoid, beta-carotene.

Volunteers absorbed large amounts of both carotenoids. The researchers concluded that tomato sauce and other tomato products made from such varieties of tomatoes could provide a way to increase the bioavailability of carotenoids in the diet.

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Tangerine Tomato

Tangerine Tomato

"A Simple Class of Photorheological Fluids: Surfactant Solutions with Viscosity Tunable by Light"

Journal of the American Chemical Society

Tapping the potential of a neglected family of "smart" fluids

In a discovery that may speed commercial and industrial uses of a third family of "smart fluids," scientists in Maryland are reporting development of new photorheological (PR) fluids that can be made simply and inexpensively. Srinivasa R. Raghavan and his students point out that electrorheological (ER) fluids and magnetoreheological (MR) fluids have found wide application in devices ranging from automobile shock absorbers and brakes to damping technology to help stabilize buildings against earthquakes.

ER and MR fluids change instantly and reversibly from a free-flowing liquid to a semi-solid with controllable strength in response to an electric or magnetic field, respectively. PR fluids are designed to accomplish the same feat using light as the trigger. They are not widely used, however, either in the lab or in industry because they are difficult and expensive to make, the researchers report in an article scheduled for the Feb. 21 issue of the Journal of the American Chemical Society.

The new PR fluids, in contrast, are based on simple, inexpensive chemicals available in most labs, say the researchers, who envision PR fluids as a technology that could enable Micro-Electro-Mechanical Systems (MEMS). Those much-discussed devices would integrate mechanical elements, sensors, actuators and electronics on chips that could revolutionize many different products.

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Subsurface oil from 1989 Alaska spill may persist for decades

Oil from the 1989 Exxon Valdez spill persists in an only slightly weathered form below the surface at some beaches along the Gulf of Alaska after 16 years and may persist for decades, researchers have concluded in a new report. It is scheduled for publication in the Feb. 15 issue of the ACS' Environmental Science & Technology, a semi-monthly journal.

The National Oceanic and Atmospheric Administration's Jeffrey W. Short and colleagues analyzed subsurface oil at 10 beaches, selected at random from among oil-contaminated areas included in their 2001 and 2005 studies. Earlier research demonstrated that buried oil could retain toxic components for years if buried in anoxic (oxygen-depleted) sediments where little decomposition from weathering occurs. The new study identified a different mechanism in which oil can be preserved in sediments that do contain oxygen. The oil persists because it exists in a thick, emulsified form sometimes termed "oil mousse" that resists weathering.

"Such persistence can pose a contact hazard to inter-tidally foraging sea otters, sea ducks, and shorebirds, create a chronic source of low-level contamination, discourage subsistence in a region where use is heavy and degrade the wilderness character of protected lands," the researchers conclude.

Environmental Science & Technology: "Slightly Weathered Exxon Valdez Oil Persists in Gulf of Alaska Beach Sediments after 16 Years"

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Debut for a "far-sighted" superlens

Amid growing excitement about experimental superlenses that are "near-sighted," researchers in California are reporting successful demonstration of a new "far-sighted" superlens with important potential scientific and industrial applications. Xiang Zhang and colleagues describe their far-field optical superlens (FSL) in an article scheduled for the Feb. 14 issue of the ACS' Nano Letters, a monthly journal.

"The far-field superlens optical imaging has great potential for many exciting applications in optical imaging, electronics manufacturing and biomedical sensing," the researchers report.

Lenses in conventional optical microscopes can produce images of objects roughly half the size of the wavelength of the light used to illuminate the object. Superlenses break that barrier, creating images of objects smaller than the wavelength of light. For optical microscopes imaging biological samples, that could mean imaging never-before-seen objects such as individual proteins traveling along the microtubules that make up a cell's skeleton and act as superhighways for molecular transport.

Zhang and colleagues point out that existing superlenses, including one developed by his group in 2005, can form an image at the near field. The new FSL image more distant objects by capturing and amplifying "evanescent" light waves that are lost in traditional lenses.

Nano Letters: "Far-Field Optical Superlens"

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Electrons travel through proteins like urban commuters
15 years of studying how electrons make their way through some important protein molecules can be summed up with an analogy: how do big city dwellers get from here to there?

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Artificial atoms make microwave photons countable
Using artificial atoms on a chip, Yale physicists have taken the next step toward quantum computing by demonstrating that the particle nature of microwave photons can now be detected.

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Neutron probe yields break in superconductor mystery
A major step toward solving a two-decades-old materials science mystery and progress toward the ultimate goal of engineering materials optimized for magnetic and electric properties.

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NIST develops rapid method for judging nanotube purity
Researchers at NIST have developed a sensitive new method for rapidly assessing the quality of carbon nanotubes.

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Standardized house dust aids health researchers
Chemists at NIST have created a standardized form of common house dust to support environmental scientists studying our everyday exposure to a catalog of potentially hazardous chemicals.

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Researchers earn $200,000 prize for filtering arsenic from water wells
International team led by Lehigh University engineer garners Silver Award in NAE's Grainger Challenge for Sustainability.

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Scientists see DNA get 'sunburned' for the first time
For the first time, scientists have observed DNA being damaged by ultraviolet (UV) light.

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Cloning the smell of the seaside
Scientists from the University of East Anglia have discovered exactly what makes the seaside smell like the seaside – and bottled it!

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Breakthrough in nanodevice synthesis revolutionizes biological sensors
A novel approach to synthesizing nanowires (NWs) allows their direct integration with microelectronic systems for the first time ...

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MIT develops nanoparticles to battle cancer
On a quest to modernize cancer treatment and diagnosis, an MIT professor and her colleagues have created new nanoparticles that mimic blood platelets ...

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Novel Ames Lab composite may replace depleted uranium
Nanostructured material offers environmentally safe armor-piercing capability.


January 2007


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Researchers probe health and safety impacts of nanotechnology
University of Florida engineering student is working on nanotechnology, but she's not seeking a better sunscreen, tougher golf club or other product - the focus of many engineers in the field.

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Testing for insulin without the pitter-patter of little feet
Journal article outlines mouse-free and animal-serum-free method of producing cruelty-free ELISA for human insulin.

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Diagnosis by patterned paper
Reasonably priced, quick and practical: Photoprinted paper supports simultaneous microscale diagnostic tests.

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Nanoengineered concrete could cut CO2 emissions
While government leaders argue about the practicality of reducing world emissions of carbon dioxide, scientists and engineers are seeking ways to make it happen.

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Surprising transition observed when flowing grains become too jam packed to move
Using color-shifting cylinders as substitutes for sand grains or coal lumps, a team of physicists has pinpointed a critical density level where granular materials suddenly cease flowing like a liquid and instead congeal into a state of rigidity.

 

ACS News:

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Eggshell-and-yolk” Nanostructures

Journal of the American Chemical Society

Toward development of an "eggshell-and-yolk" anticancer nanomedicine

Scientists in Hong Kong are reporting synthesis and early laboratory tests of a new nanostructure that they believe may lead to the design of an anticancer nanomedicine. In a study scheduled for publication in the Feb. 21 issue of the weekly Journal of the American Chemical Society, Bing Xu and colleagues describe the structure as an eggshell nanocrystal.

Like a chicken’s egg, the structure has an outer shell that encloses a "yolk" that can be released from the shell. In their experiments, the researchers used a yolk consisting of iron and platinum, the metal responsible for the activity of the widely used chemotherapeutic drug, cisplatin. Cultures of human cancer cells took up the nanostructures and the nanostructures released their yolks, which proved to have "exceptionally high toxicity" for the cancer cells.

"This type of yolk-shell nanostructures may lead to novel nanomedicine for treating cancers," the researchers state, describing nanostructures that may be coated with antibodies that specifically target cancer cells and thus reduce body-wide side effects that occur with traditional chemotherapeutic drugs.

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Dyed Wheat Gluten Fibers

Biomacromolecules

Spinning wheat

Smooth as silk. Warm as wool;  ... as wheat gluten. Marketing specialists may be challenged to fill in that blank in the future, now that scientists in Nebraska report the first successful production of high-quality fibers from wheat gluten, that grain’s major protein. In an article scheduled for the Feb. 12, issue of ACS’ Biomacromolecules, a monthly journal, they describe the new fibers as having mechanical properties similar to wool. Some of the properties of wheat gluten fibers also are superior to soy protein and casein materials intended for biomedical applications, the report states.

Wheat gluten fibers would have a major cost advantage over both wool and silk, the two existing commercial natural protein fibers, according to the researchers. While wool sells for about $5-$8 per pound, and silk for $10-$14 per pound, wheat gluten fetches less than 50 cents per pound and huge quantities are available worldwide.

The report describes recent efforts to produce commercial quantities of fiber from milk, corn, peanut and other proteins. "Unfortunately, none of these attempts have been commercially successful to produce 100 percent protein fibers mainly due to the high cost and poor quality of the fibers," the report adds. It includes a description of the properties of wheat gluten fibers and images of fiber strands.

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New method for detecting fake drugs without opening the package

With sale of counterfeit drugs causing major problems around the world, scientists in the United Kingdom are reporting development of a new way of identifying fake pills and capsules without opening the product package. In a report scheduled for the March 1 issue of ACS’ Analytical Chemistry, a semi-monthly journal, Pavel Matousek and Charlotte Eliasson describe the growing need for non-invasive verification of the authenticity of pharmaceutical products.

The report notes, for instance, that large quantities of counterfeit drugs have been withdrawn from the market in recent years in the United States and the U. K., with fake anti-malaria drugs causing a major crisis in eastern Asia. Verification can be difficult, the researchers explain, because medications must be analyzed without opening the product package. Once a drug package is open, the product usually cannot be marketed.

The investigators describe development of a new form of Raman spectroscopy, a mainstay tool for identifying molecules, which can probe deep layers of material that are well beyond the reach of conventional Raman spectroscopy. The method, spatially offset Raman spectroscopy, can analyze through paper packaging, plastic containers, capsule shells, and tablet coatings to verify the ingredients in a pharmaceutical product, the researchers state.

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Most Comprehensive-Ever Survey of Flavonoids in U. S. Foods

Scientists studying the health benefits of flavonoids — those disease-preventing compounds in fruits, vegetables, wine, dark chocolate and other foods — finally have comprehensive data on flavonoid levels in foods consumers buy in the United States. The U. S. Department of Agriculture’s James M. Harnly and colleagues are unveiling new flavonoid data collected from the first systematic sampling of foods designed specifically to characterize flavonoids. The report appeared in the Jan. 10 issue of the ACS’ Journal of Agricultural and Food Chemistry, a bi-weekly publication.

The report notes that interest in the flavonoid content of foods dates to the early 1980s. Since then, two databases had been compiled on levels of these compounds in common foods; the first based on a critical evaluation of flavonoid data in the literature and the second based on the analysis of proanthocyanidins found in selected foods. The reported data have been combined with the literature database.

For the latest report, researchers determined levels of 20 flavonoids in more than 60 fresh fruits, vegetables and nuts collected at two different times of the year from commercial markets in four regions of the United States. Researchers analyzed an average of five samples for each food. Complete results are included in the article. They found flavonoid levels that compared well with the literature database, but the catechins were generally lower in fruits and nuts than the figures reported in the proanthocyanidin database. The new study found a high variability in the flavonoid content of food samples.

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DNA gets new twist: Carnegie Mellon scientists develop unique 'DNA nanotags'
Ultra-bright fluorescent labels are important for biomedical applications.

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Novel laboratory technique nudges genes into activity
A new technique that employs RNA, a tiny chemical cousin of DNA, to turn on genes could lead to therapeutics for conditions in which nudging a gene awake would help alleviate disease.

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Coated nanoparticles solve sticky drug-delivery problem
Researchers take cues from viruses to get treatment through body's protective.

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A boost for hydrogen fuel cell research
The development of hydrogen fuel cells for vehicles, the ultimate green dream in transportation energy, is another step closer ...

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Weizmann Institute scientists develop the first molecular keypad lock
Molecular keypad inputs consist of iron ions, acids, bases and ultraviolet light.

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Canadian researchers first to complete the human metabalome
Researchers have announced the completion of the first draft of the human metabolome, the chemical equivalent of the human genome.

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Chemists report important step toward building molecular computers
A team of UCLA and California Institute of Technology chemists reports in the Jan. 25 issue of the journal Nature the successful demonstration of a large-scale, "ultra-dense" memory device that stores information using reconfigurable molecular switches.

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Porous media and its applications in science, engineering and industry
Second international conference on porous media.

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Hydrogen-powered lawnmowers?
New design could open door to small-scale fuel cells.

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Turning an axel mounted molecular wheel
Researchers have, for the first time, managed to control the rotation of a wheel in a molecule.

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Light-emitting diodes for night-vision displays
Redder than red: Porphyrin complex used as doping agent in highly efficient infrared-light-emitting diodes.

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UIC receives grant to find new drugs for bipolar disorder
Researchers at the University of Illinois at Chicago have been awarded a three-year $2.1 million grant from the National Institute of Mental Health to develop a new drug to treat bipolar disorder.

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System detects hazardous, toxic material in concealed packaging
Sandia develops next generation of screening devices.

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Research to spotlight carbon monoxide benefits
Scientists at the University of York have won a grant of £110,000 to investigate potential uses of carbon monoxide in treating disease.

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Nano world off the radar for most
Sunscreens contain nano particles, carbon and titania nanotubes show promise and nano structures are the rage in engineering schools. While the proliferation of nano research may signal a mini revolution, outside the realms of business and science, this insurgency may be no more than a whisper, according to an international team of researchers.

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Iowa State corn/soy plastics to be made into hog feeders
Richard Larock sorted through a pile of neatly labeled baggies filled with the plastics he makes from corn, soybean and other bio-based oils.

 

ACS News:

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Toward medical implants with an antibiotic coating

The search for ways to protect polymer-based medical implants - used in devices ranging from contact lenses to artificial hearts, as well as surgical devices and operating room equipment - from bacterial infections has led scientists in Mississippi to develop a penicillin-coated version of a key polymer biomaterial ...

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An advance in mimicking Mother Nature

Birds use them to reduce the weight of their feathers. Polar bears rely on them to keep warm in the Arctic cold. Now scientists in China report what they believe to be the first easy, straightforward method for making the kind of multi-channel microtubes found in birds, polar bears and other animals.

Lei Jiang, Xinyu Cao and Yong Zhao describe the new electrojet spinning technique in an article scheduled for the Feb. 7 issue of the Journal of the American Chemical Society, a weekly publication. The advance in biomimic materials - a field that aims to copy useful features found in nature - could be used to produce super-lightweight and extraordinarily warm textiles, multi-component drug deliver devices, highly efficient catalysts and other commercial products, according to the scientists.

"We have developed a very simple and powerful multifluidic compound-jet electrospinning technique for fabricating biomimic multichannel microtubes that have been seldom obtained with other methods," they note. The researchers used the new spinning process to make tubes with 2, 3, 4 and 5 separate interior channels. In addition to offering multiple channels in one tube, the structures promise to be stronger with other advantages over single-channel microtubes, the report indicates.

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New drugs awaiting discovery in Chinese herbs?

The first large-scale computer screenings of Chinese herbs - commonly used in traditional Chinese medicine - has revealed a wide variety of compounds with potential for use in treating HIV/AIDS, cancer, Alzheimer's Disease, arthritis and other diseases, according to scientists in London.

In an article scheduled for the March 26 issue of the ACS' Journal of Chemical Information and Modeling, a bi-monthly publication, David J. Barlow and colleagues note that such in silico research is becoming increasingly effective in identifying promising compounds that could be candidates for drug development. In silico ("in silicon") means research done on computers or via computer simulation and has joined the in vivo and in vitro experiments traditionally used in the life sciences.

The researchers screened a database of chemical structures of Chinese herbal constituents from 240 species of plants for possible activity against various diseases. About 62 percent of the species were found to contain chemicals with characteristics required for activity against at least one disease and 53 percent against two or more diseases. The study also describes corroborative evidence from the scientific literature that supported many of the computer predictions. In a companion article in the journal, the researchers describe the herbal databases.

Virtual Screening of Chinese Herbs with Random Forest

Phytochemical Databases of Chinese Herbal Constituents and Bioactive Plant Compounds with Known Target Specificities

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Questioning the safety of blower-equipped carbon canister breathing devices

A new study raises questions about the safety of the growing trend toward equipping carbon canister protective breathing devices with a blower device to enable personnel to breathe easier ...

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Al4H6 - Researchers create new class of compounds
Researchers create new class of compounds. May have applications in solid rocket fuel and the hydrogen economy.

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New quartz references for workplace safety
Chemists at NIST have developed a new set of reference materials that could contribute to significant improvements in workplace safety through more accurate measurement of the amount of quartz dust in the air.

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Walking molecule now carries packages
Molecule walks in a straight line and carries a tiny shopping bag in each hand.

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Buckyballs used as 'passkey' into cancer cells
Drug delivery study pairs Rice chemists with BCM pediatricians.

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Improved nanodots could be key to future data storage
Researchers have made nanodot arrays that respond to magnetic fields with record levels of uniformity.

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Scientists discover way to order polar molecules in crystals
The discovery has implications for future of telecommunications and computing.

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Rotting leaf litter study could lead to more accurate climate models
Bags of decomposing organic matter have allowed a research team to produce an elegant and simple set of equations to calculate the nitrogen released into the soil during decomposition, which in turn could significantly improve the accuracy of global climate change models.

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New miniaturized device for lab-on-a-chip separations
Researchers have developed an elegantly simple, miniaturized technique for rapidly separating minute samples of proteins, amino acids and other chemical mixtures. A low-cost prototype device can run up to eight separations simultaneously in a space about the size of a quarter, highlighting the technique's potential for use in microfluidic "lab-on-a-chip" systems.

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Algae toxin identification unravels fish-kill mystery

A team of researchers from the Hollings Marine Laboratory in Charleston, S.C., has uncovered a subtle chemical pathway by which a normally inoffensive algae, Pfiesteria piscicida, can suddenly start producing a lethal toxin. The discovery, reported last week in Environmental Science and Technology, could resolve a long-standing mystery surrounding occasional mass fish kills on the East Coast.

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Prussian Blue for information storage
In the family of Prussian blue, there is a compound that can act as a switch: it is not magnetic at the outset, but it can become magnetized by the effect of light and return to its initial state by heating ...

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A new generation of medicinal products
The team led by Didier Bourissou has managed to develop a novel synthetic process for materials which significantly increases their diversity.

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New way to produce multilayer cobalt thin films for technical and scientific applications
Voltammetric study of underpotential deposition of cobalt onto a glassy carbon electrode.

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Water theory is watertight, researchers say
There may be tiny bubbles in the wine, but not at the interface between water and a waxy coating on glass, a new study shows.

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Study looks to bring the high properties of metallic glass materials to bulk production - Effect of titanium in Cu-Hf based bulk metallic glasses.

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Lead with a Poisonous Electron Shield
A free pair of electrons may be the source of lead’s toxicity.

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Physicists Discover Structures of Gold Nanoclusters

Using different experimental techniques, two separate and independent research groups in collaboration with a team from the Center for Computational Materials Science (CCMS) at the Georgia Institute of Technology, have unveiled the size-dependent evolution of structural and electronic structural motifs of gold nanoclusters ranging in size from 11 to 24 atoms. The experiments, in conjunction with the theoretical analysis performed by the Georgia Tech team, show near perfect agreement pertaining to the cluster structures occurring in the experiments.

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Dual enzymatic activity of RECQ1 explained by different quaternary structures
Researchers are describing two structural forms of the human RECQ1 helicase, a large oligomeric complex composed of five or six subunits and a smaller form consistent with only one or two molecules.

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New Function of Cardiac Sodium Pump
Scientists at the Max Delbrόck Center for Molecular Medicine (MDC) Berlin-Buch have discovered a new function of the sodium pump.

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Destructive Enzyme Shows A Benevolent Side
New research shows that a recently discovered enzyme that destroys the messenger RNA (mRNA) for some proteins can also help to protect the mRNA during times of stress.

 

ACS News:

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Mixing it up with E. coli
Poetry in motion may seem like an odd way to describe swimming bacteria, but that's what researchers at Drexel University got when they enlisted Escherichia coli (E. coli) in an effort to tackle a major problem in developing lab-on-a-chip technology ...

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Closing a loophole in the RNA World Hypothesis
New scientific research may close a major loophole in the RNA world hypothesis, the idea that ribonucleic acid - not the fabled DNA that makes up genes in people and other animals - was the key to life's emergence on Earth 4.6 billion years ago. That hypothesis states that RNA catalyzed all the biochemical reactions necessary to produce living organisms. Only later were those self-replicating RNA units joined by organisms based on DNA, which evolved into more advanced forms of life ...

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Uncovering a new reason why patients respond differently to the same drug dose
Why does the standard dose of certain medications prove dangerously high for some patients and too low to produce beneficial effects in others? Scientists have added a previously unrecognized factor to the list of explanations (such as age, gender, diet and genetics) for this common problem of individual variability in response to drugs ...

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An ingenious new delivery system for antioxidant SOD
Scientists in Georgia are reporting successful lab tests of new polymer microparticles that show promise as a long-sought way to deliver drugs directly into the cell structures responsible for inflammation. Those immune system structures, macrophages, devour and destroy foreign substances such as invading bacteria and cellular debris. However, they also release so-called reactive oxygen species that help cause arthritis, acute liver failure and other inflammatory diseases ...

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Brookhaven lab scientists stabilize platinum electrocatalysts for use in fuel cells

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Spanish scientists reveal dynamic map of proteins
Scientists have published a provisional “atlas” of the dynamic behaviour of proteins in the prestigious scientific journal, Proceedings of the National Academy of Sciences USA.

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Converting Nitrogen to a More Useful Form
Nitrogen fixation: Hafnium complex couples atmospheric nitrogen with carbon dioxide.

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New study sheds light on 'dark states' in DNA
Chemists at Ohio State University have probed an unusual high-energy state produced in single nucleotides - the building blocks of DNA and RNA - when they absorb ultraviolet (UV) light.

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Public shares views on environmental, health and safety research needs for nanoscale materials

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Hybrid structures combine strengths of carbon nanotubes and nanowires

New wires could create better nanotube interconnects and devices

A team of researchers at Rensselaer Polytechnic Institute has created hybrid structures that combine the best properties of carbon nanotubes and metal nanowires.

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Turning green gunk to gold, anti-cancer gold
Combining synthetic chemistry techniques with a knowledge of the properties and actions of enzymes, scientists have been able to produce an exciting class of anti-cancer drugs originally isolated from blue-green algae.

 

ACS News:

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The first molecular keypad lock
How can defense or intelligence agencies safeguard the security of top-secret data protected by a computation device the size of a single molecule?

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Inhalation of golf course pesticides in northeast poses "minimal" health risk
When golfers in the northeastern United States dream of returning to those greens and fairways next spring, they can have some reassurance that inhaling pesticides applied to the turf does not pose a serious human health threat, a new study suggests.

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A New Family of Lead-Free Optical Glasses
With environmental regulations forbidding the use of lead in consumer products, scientists in Canada have developed, synthesized and tested a new family of special optical glasses that contain no lead but perform like traditional lead-based optical glass.

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Rapid, Low-Cost DNA Testing
Improving Health & Catching Criminals

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Nanoscale cubes and spheres - Uniform porous silicon oxide nano-objects formed by controlled disassembly of a lattice structure.

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Cheaper LEDs from breakthrough in zinc oxide (ZnO) nanowire research

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Repetitive motion speeds nanoparticle uptake
'Bucky amino acid' penetrates faster, deeper when skin is flexed.

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UD scientists discover new class of polymers

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European Union outpaces United States on chemical safety
Recently, the European Union has adopted some of the world's strictest policies on e-waste and potentially hazardous chemicals.

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USC team reveals structure of APOBEC family protein
Study sheds new light on rare immunodeficiency disease

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Joining forces
Weizmann Institute scientists use peptides and lipopeptides to fight bacteria


 
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Subject category: Chemistry news archive 2007

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